Blend membrane of succinic acid-crosslinked chitosan grafted with heparin/PVA-PEG (polyvinyl alcohol-polyethylene glycol) and its characterization

Surface Adsorption of Polyethylene Glycol and Polyvinyl Alcohol with Variable Molecular Weights on Zinc Oxide Nanoparticles

Immunogenicity of Polyethylene Glycol (PEG)

Covalent attachment of polyethylene glycol (PEG) to active proteins (PEGylation technology) successfully generated several FDA-approved compounds, including four blockbusters, which are considered non immunogenic. However, PEG antibodies and intolerance to the infusion were reported in some patients with gout treated with pegloticase, a PEG-uricase recently approved by the FDA (Food and Drug Ad...

Fabrication and characterization of methylene-blue-doped polyvinyl alcohol-polyacrylic acid blend for holographic recording.

A methylene-blue-sensitized polymer blend of polyvinyl alcohol and polyacrylic acid is fabricated and tested for holographic recording. It was found to have good characteristics such as high sensitivity, storage stability, ease of fabrication, and environmental stability. Optimization of the ratio of polyvinyl alcohol/polyacrylic acid, the sensitizer concentration, pH, energy, diffraction effic...

Chitosan-acryl amide grafted polyethylene glycol interpenetrating polymeric network for controlled release studies of Cefotaxime

The aim of this present study was to develop a pH sensitive interpenetrating polymeric network (IPN) hydro gels (HG) based on chitosan-acryl amide-grafted-poly ethylene glycol (CTS-AM-PEG) followed by hydrolysis that are cross-linked with glutaraldehyde (GA). Cefotaxime is an antibiotic drug was successfully loaded in these IPNHG’s. The HGs formed were characterized by Fourier transform infrare...

Improvement of curcumin solubility by polyethylene glycol/chitosan-gelatin nanoparticles (CUR-PEG/CS-G-nps)

Curcumin (CUR), a yellow polyphenol compound is reportedly associated with a diverse therapeutic potential. Despite all curative properties of CUR, its usage in oral administration is restricted due to low bioavailability, low aqueous solubility and poor absorption rate. The aim of this study was to develop a nontoxic nanocurcumin (CUR-NPs) with enhanced bioavailability. For this reason, the CU...